Succinate

ChemistryAlso known as: Succinic acidAlso known as: Butanedioic acidµmol/L

Measures the level of succinate, an organic acid involved in energy production.

Normal Range

4 – 20 µmol/L

µmol/L

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Elevated succinate suggests mitochondrial dysfunction or impaired cellular energy metabolism. This finding can guide targeted interventions to improve energy production and metabolic health.

Understanding Your Results

Normal Range

4 – 20 µmol/L

Overview

Succinate is an organic acid and key player in cellular energy production (the citric acid cycle). Elevated blood succinate may indicate mitochondrial dysfunction, metabolic disease, or impaired energy metabolism. This test is used in functional and metabolic medicine to assess cellular respiration and identify metabolic bottlenecks. Abnormal levels can guide dietary, supplement, or lifestyle interventions to restore energy production.

Research & Evidence

100 publications

Sort:

Succinate Dehydrogenase A-Deficient Renal Cell Carcinoma with Predominantly Papillary Structures: A Case Report and Review of the Literature.

Int J Surg Pathol · 2025

PMID: 40827068Other

Skeletal muscle morphology and metabolism in patients with heart failure compared to healthy controls: a systematic review and meta-analysis.

J Appl Physiol (1985) · 2026

PMID: 41665168

Priming Effects on Soil Organic Matter Mineralization by Carbon Substrates: A Global Meta-Analysis.

Glob Chang Biol · 2026

PMID: 41964211

The role and therapeutic potential of succinate and succinylation in cardiovascular diseases.

Clin Epigenetics · 2026

PMID: 41872972

Metabolic rewiring through succinate-GPR91 signaling: a fresh perspective on HFpEF energetics.

Cardiovasc Diabetol · 2026

PMID: 41872865

Enarodustat combined with oral iron supplementation for iron-deficient non-dialysis-dependent chronic kidney disease anemia patients: Synergistic effects and safety.

Medicine (Baltimore) · 2026

PMID: 41961655

Continuous Manufacturing of Controlled-Release Metoprolol Succinate Tablets by Novel Hot-Melt Fragmentation Technology.

AAPS PharmSciTech · 2026

PMID: 41927858

Gastrointestinal Stromal Tumor: History, Molecular Subtypes, and Risk Stratification.

J Gastric Cancer · 2026

PMID: 41942355

The metabolic profiles of cancer stem cells.

Stem Cell Res Ther · 2026

PMID: 41975495

The Induction of Succinate Dehydrogenase of "C1" Conformation and the Difference in Its Binding to Fungicides Lead to the Variation in Toxicity of SDHI Fungicides Against.

J Agric Food Chem · 2026

PMID: 41874210

Research data from MEDLINE/PubMed · 100 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

35871-3Primary

Succinate [Moles/volume] in Serum or Plasma

umol/L

26798-9

Succinate [Presence] in Urine

Available Lab Tests

Order tests that measure this biomarker

Urinary Organic Acids

Results in 7-14 business days