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LEANN NITSCHKE, MD
MD
Surgery Physician
NPI: 1114010659Individual
Specialties, Licenses & Credentials
Surgery PhysicianPrimary
Surgery
Code: 208600000X
30476 020(WI)
Research & Publications (20)
CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions.
PMID 19594633·Immunol Rev·2009
6-review
Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system.
PMID 18669487·Brain·2008
7-preclinical
Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.
PMID 17767948·J Allergy Clin Immunol·2008
7-preclinical
Regulation of repertoire development through genetic control of DH reading frame preference.
PMID 19050259·J Immunol·2008
7-preclinical
IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta.
PMID 17420268·J Exp Med·2007
7-preclinical
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.
PMID 17600736·Immunity·2007
7-preclinical
Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.
PMID 17572677·Nat Immunol·2007
7-preclinical
Expression of aberrant forms of CD22 on B lymphocytes in Cd22a lupus-prone mice affects ligand binding.
PMID 16291654·Int Immunol·2006
7-preclinical
Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes.
PMID 16342234·Eur J Immunol·2006
7-preclinical
B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate.
PMID 16455997·J Immunol·2006
7-preclinical
Regulation of B cell development and B cell signalling by CD22 and its ligands alpha2,6-linked sialic acids.
PMID 16497829·Int Immunol·2006
7-preclinical
Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.
PMID 16754718·J Exp Med·2006
7-preclinical
The role of CD22 and other inhibitory co-receptors in B-cell activation.
PMID 15886119·Curr Opin Immunol·2005
6-review
A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function.
PMID 16272317·J Immunol·2005
7-preclinical
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice.
PMID 15814705·J Immunol·2005
7-preclinical
A critical role for Fc gamma RIIB in the induction of rheumatoid factors.
PMID 15383609·J Immunol·2004
7-preclinical
Molecular interactions regulate BCR signal inhibition by CD22 and CD72.
PMID 15364057·Trends Immunol·2004
6-review
The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.
PMID 15048729·Eur J Immunol·2004
4-observational
The role of B cell CD22 expression in Staphylococcus aureus arthritis and sepsis.
PMID 15050965·Microbes Infect·2004
7-preclinical
B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling.
PMID 14635051·Eur J Immunol·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 8780 LINCOLN STREET
SAVAGE, MD 20763 - Phone
- (212) 782-7993
Quick Facts
- NPI
- 1114010659
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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