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ROWA ATTAR, MD
MD
Cardiovascular Disease Physician
NPI: 1114596996Individual
Specialties, Licenses & Credentials
Cardiovascular Disease PhysicianPrimary
Internal Medicine — Cardiovascular Disease
Code: 207RC0000X
BP10070992(TX)
Research & Publications (20)
Prostaglandin E2 via steroidogenic factor-1 coordinately regulates transcription of steroidogenic genes necessary for estrogen synthesis in endometriosis.
PMID 19001523·J Clin Endocrinol Metab·2009
8-other
Can pentoxifylline improve the sperm motion and ICSI success in the primary ciliary dyskinesia?
PMID 18461343·Arch Gynecol Obstet·2009
5-case
BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells.
PMID 19118050·Clin Cancer Res·2009
8-other
The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors.
PMID 19117999·Cancer Res·2009
8-other
Castration-resistant prostate cancer: locking up the molecular escape routes.
PMID 19447877·Clin Cancer Res·2009
6-review
Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer.
PMID 19654297·Cancer Res·2009
7-preclinical
Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors.
PMID 18572407·Bioorg Med Chem Lett·2008
8-other
Use of hematopoietic stem cells in obstetrics and gynecology.
PMID 18539082·Transfus Apher Sci·2008
6-review
Knowledge and interest of Turkish women about cervical cancer and HPV vaccine.
PMID 18386470·Eur J Gynaecol Oncol·2008
8-other
The current state of preclinical prostate cancer animal models.
PMID 18213636·Prostate·2008
4-observational
HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.
PMID 18765823·Mol Cancer Ther·2008
8-other
The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens.
PMID 18218096·BMC Cell Biol·2008
8-other
2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924.
PMID 18258427·Bioorg Med Chem Lett·2008
7-preclinical
Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.
PMID 18291644·Bioorg Med Chem Lett·2008
7-preclinical
Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors.
PMID 19001433·Mol Cancer Ther·2008
8-other
Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activity.
PMID 18763755·J Med Chem·2008
7-preclinical
Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
PMID 17317169·Bioorg Med Chem Lett·2007
8-other
Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase.
PMID 17187980·Bioorg Med Chem Lett·2007
7-preclinical
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail.
PMID 17296734·Mol Cell Biol·2007
7-preclinical
Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile.
PMID 17398093·Bioorg Med Chem Lett·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 6550 FANNIN ST, SMITH TOWER, SUITE 1901
HOUSTON, TX 77030 - Phone
- (713) 441-1100
Quick Facts
- NPI
- 1114596996
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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