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MATTHEW THREADGILL, M.D.
M.D.
Pediatrics Physician
NPI: 1376740977Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
002452(GA)
Research & Publications (20)
Effect of poly (ADP-ribose) polymerase-1 inhibition on the proliferation of murine colon carcinoma CT26 cells.
PMID 18989759·Pathol Oncol Res·2009
7-preclinical
Design, synthesis, and evaluation in vitro of quinoline-8-carboxamides, a new class of poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) inhibitor.
PMID 19117416·J Med Chem·2009
8-other
Synthesis and use of isotope-labelled substrates for a mechanistic study on human alpha-methylacyl-CoA racemase 1A (AMACR; P504S).
PMID 19156321·Org Biomol Chem·2009
8-other
Poly(ADP-ribose) polymerase inhibition down-regulates expression of metastasis-related genes in CT26 colon carcinoma cells.
PMID 19468250·Pathobiology·2009
7-preclinical
Extraction, structural characterisation and evaluation of hydroxycinnamate esters of orchard grass (Dactylis glomerata) as substrates for polyphenol oxidase.
PMID 18929376·Phytochemistry·2008
8-other
Alpha-methylacyl-CoA racemase--an 'obscure' metabolic enzyme takes centre stage.
PMID 18279392·FEBS J·2008
6-review
Influence of 5-aminoisoquinolin-1-one (5-AIQ) on neutrophil chemiluminescence in rats with transient and prolonged focal cerebral ischemia and after reperfusion.
PMID 19212013·J Physiol Pharmacol·2008
7-preclinical
Characterisation of recombinant human fatty aldehyde dehydrogenase: implications for Sjögren-Larsson syndrome.
PMID 18035827·J Enzyme Inhib Med Chem·2007
8-other
Formation of 3-aryl-5-nitroisocoumarins from 5-nitroisocoumarins and aromatic acyl chlorides under Friedel-Crafts conditions.
PMID 17715975·J Org Chem·2007
8-other
Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis.
PMID 17451962·Bioorg Med Chem·2007
8-other
Synthetic approaches to peptides containing the L-Gln-L-Val-D(S)-Dmt motif.
PMID 17376694·Bioorg Med Chem·2007
8-other
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
PMID 15452194·J Pharmacol Exp Ther·2005
7-preclinical
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
PMID 15644425·J Pharmacol Exp Ther·2005
4-observational
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.
PMID 14717920·Kidney Int·2004
7-preclinical
5-Aminoisoquinolinone reduces colon injury by experimental colitis.
PMID 15599708·Naunyn Schmiedebergs Arch Pharmacol·2004
4-observational
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.
PMID 15178366·Eur J Pharmacol·2004
7-preclinical
Synthesis of N-benzyl- and N-phenyl-2-amino-4,5-dihydrothiazoles and thioureas and evaluation as modulators of the isoforms of nitric oxide synthase.
PMID 12951150·Bioorg Med Chem·2003
7-preclinical
Synthesis of meso-substituted porphyrins carrying carboranes and oligo(ethylene glycol) units for potential applications in boron neutron capture therapy.
PMID 12929426·Org Biomol Chem·2003
8-other
Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline.
PMID 14552756·Bioorg Med Chem Lett·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1245 AUGUSTA WEST PKWY
AUGUSTA, GA 30909 - Phone
- (706) 868-0389
Quick Facts
- NPI
- 1376740977
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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