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DON CHAPLIN, M.D.
M.D.
Internal Medicine Physician
NPI: 1386671972Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
16884(NC)
Research & Publications (20)
Current development status of small-molecule vascular disrupting agents.
PMID 16784022·Curr Opin Investig Drugs·2006
6-review
Drug based approaches for targeting tumor vasculature: development of combretastatin A4 phosphate.
PMID 12954990·Pathophysiol Haemost Thromb·2003
7-preclinical
Selective induction of tumor ischemia: development of vascular targeting agents for cancer therapy.
PMID 12498016·Curr Opin Investig Drugs·2002
6-review
The development of combretastatin A4 phosphate as a vascular targeting agent.
PMID 12459376·Int J Radiat Oncol Biol Phys·2002
7-preclinical
A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P).
PMID 19236265·Expert Opin Investig Drugs·2009
6-review
The lymphotoxin LTalpha(1)beta(2) controls postnatal and adult spleen marginal sinus vascular structure and function.
PMID 19303389·Immunity·2009
7-preclinical
MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways.
PMID 19593770·Eur J Immunol·2009
7-preclinical
Development of synthetic methodology suitable for the radiosynthesis of combretastatin A-1 (CA1) and its corresponding prodrug CA1P.
PMID 19161336·J Nat Prod·2009
7-preclinical
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
PMID 18157131·Nat Immunol·2008
7-preclinical
The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death.
PMID 18024794·Blood·2008
8-other
Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents.
PMID 18303849·J Nat Prod·2008
7-preclinical
Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.
PMID 18710804·Bioorg Med Chem Lett·2008
8-other
Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology.
PMID 18436651·Proc Natl Acad Sci U S A·2008
7-preclinical
Intraclonal competition inhibits the formation of high-affinity antibody-secreting cells.
PMID 18941192·J Immunol·2008
7-preclinical
Quality of life after liver transplantation for hepatitis C infection.
PMID 17665316·Qual Life Res·2007
8-other
Combination chemotherapy including combretastatin A4 phosphate and paclitaxel is effective against anaplastic thyroid cancer in a nude mouse xenograft model.
PMID 17550961·J Clin Endocrinol Metab·2007
7-preclinical
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.
PMID 16990548·Science·2006
7-preclinical
Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice.
PMID 16651610·Am J Pathol·2006
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1234 HUFFMAN MILL RD
BURLINGTON, NC 27215 - Phone
- (336) 538-1234
Quick Facts
- NPI
- 1386671972
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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