Back to Search
LESLEY PEARL, PH.D.
PH.D.
Mental Health Counselor
NPI: 1548201056Individual
Specialties, Licenses & Credentials
Mental Health CounselorPrimary
Counselor — Mental Health
Code: 101YM0800X
11593(NY)
Research & Publications (20)
A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s.
PMID 19032597·FEBS J·2009
8-other
Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
PMID 19446481·Mol Cell·2009
8-other
Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2.
PMID 19394299·Mol Cell·2009
8-other
Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90.
PMID 19631219·J Mol Biol·2009
8-other
Structural basis of the radicicol resistance displayed by a fungal hsp90.
PMID 19236053·ACS Chem Biol·2009
8-other
Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.
PMID 19155274·Nucleic Acids Res·2009
8-other
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.
PMID 18922470·Mol Cell·2008
8-other
Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair.
PMID 18676809·Genes Dev·2008
8-other
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
PMID 18413753·Cancer Res·2008
7-preclinical
Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
PMID 18800759·J Med Chem·2008
8-other
The Hsp90 molecular chaperone: an open and shut case for treatment.
PMID 18290764·Biochem J·2008
6-review
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
PMID 18020435·J Med Chem·2008
7-preclinical
Molecular characterization of macbecin as an Hsp90 inhibitor.
PMID 18357975·J Med Chem·2008
7-preclinical
Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes.
PMID 18818696·EMBO J·2008
8-other
Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.
PMID 18239682·EMBO J·2008
8-other
The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis.
PMID 18256191·Development·2008
7-preclinical
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
PMID 17431102·Mol Cancer Ther·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 19 HILL ST
GOSHEN, NY 10924 - Phone
- (845) 294-9139
Quick Facts
- NPI
- 1548201056
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
Are you this provider?
Claim Your Profile