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R SEARS, MD
MD
Internal Medicine Physician
NPI: 1649283136Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
ME84364(FL)
Research & Publications (20)
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc.
PMID 19131971·EMBO J·2009
8-other
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling.
PMID 19028839·FASEB J·2009
8-other
A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.
PMID 18246411·Cancer Metastasis Rev·2008
6-review
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data.
PMID 19055840·BMC Bioinformatics·2008
8-other
Combining control input with flight path data to evaluate pilot performance in transport aircraft.
PMID 18998489·Aviat Space Environ Med·2008
8-other
Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens.
PMID 18000048·Proc Natl Acad Sci U S A·2007
7-preclinical
A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast.
PMID 17192266·J Biol Chem·2007
8-other
Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
PMID 17297438·Oncogene·2007
7-preclinical
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
PMID 17646409·J Exp Med·2007
8-other
Leptin receptor signaling in midbrain dopamine neurons regulates feeding.
PMID 16982424·Neuron·2006
7-preclinical
Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias.
PMID 16855632·Leukemia·2006
8-other
Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.
PMID 16537924·Mol Cell Biol·2006
8-other
A general synthesis of tris-indole derivatives as potential iron chelators.
PMID 18007320·Molecules·2005
8-other
The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance.
PMID 15772353·J Neurosci·2005
4-observational
Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.
PMID 16363065·J Investig Dermatol Symp Proc·2005
6-review
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
PMID 15048125·Nat Cell Biol·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 540 THE RIALTO
VENICE, FL 34285 - Phone
- (941) 480-2800
Quick Facts
- NPI
- 1649283136
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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