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JOHN WITHERINGTON, MD
MD
Internal Medicine Physician
NPI: 1720008709Individual
Specialties, Licenses & Credentials
Emergency Medicine Physician
Emergency Medicine
Code: 207P00000X
MD0000014835(TN)
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
MD141835(TN)
Research & Publications (20)
Cognitive enhancing effects of ghrelin receptor agonists.
PMID 19652956·Psychopharmacology (Berl)·2009
7-preclinical
5-hydroxyindalpine, an agonist at the putative 5-HT receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon.
PMID 19309442·Neurogastroenterol Motil·2009
7-preclinical
Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor.
PMID 19128969·Bioorg Med Chem Lett·2009
7-preclinical
Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation.
PMID 18694442·Neurogastroenterol Motil·2009
7-preclinical
Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
PMID 18316188·Bioorg Med Chem Lett·2008
7-preclinical
Therapeutic approaches towards the treatment of gastroinstestinal disorders.
PMID 17440638·Drug News Perspect·2007
7-preclinical
Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification.
PMID 17942309·Bioorg Med Chem Lett·2007
4-observational
GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.
PMID 17327487·J Pharmacol Exp Ther·2007
7-preclinical
Pyridone derivatives as potent and selective VLA-4 integrin antagonists.
PMID 16455247·Bioorg Med Chem Lett·2006
8-other
Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin.
PMID 16182445·Neurosci Lett·2006
4-observational
Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat.
PMID 16873401·J Physiol·2006
7-preclinical
Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists.
PMID 16931004·Bioorg Med Chem Lett·2006
7-preclinical
Organolithium-induced alkylative ring opening of aziridines: synthesis of unsaturated amino alcohols and ethers.
PMID 17064027·J Org Chem·2006
8-other
(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitors.
PMID 15950465·Bioorg Med Chem Lett·2005
8-other
Challenges facing drug discovery in vascular disease.
PMID 16491168·Drug News Perspect·2005
7-preclinical
Unsaturated 1,2-amino alcohols and ethers from aziridines and organolithiums.
PMID 15467888·Chem Commun (Camb)·2004
8-other
6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).
PMID 12941332·Bioorg Med Chem Lett·2003
7-preclinical
5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).
PMID 12699759·Bioorg Med Chem Lett·2003
4-observational
5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).
PMID 12699760·Bioorg Med Chem Lett·2003
4-observational
CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.
PMID 12954060·J Med Chem·2003
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 6570 HERONSWOOD DR
MEMPHIS, TN 38119 - Phone
- (901) 842-1473
Quick Facts
- NPI
- 1720008709
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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